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What Do Alcoholic Handrubs Contain?

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Alcoholic handrubs are the primarily recommended hand hygiene tools according to all large professional organizations. (ABHR = Alcohol-based handrub, according to the WHO terminology.) These contain alcohol as active ingredient;  ethanol ,  propan-1-ol ,  propan-2-ol  or the combination of these. These three alcohols have several alternative names, some may sound more familiar: the alternative names are listed in  Figure 1 , along with their chemical structures. Figure 1 : Structure of ethanol, propan-1-ol and propan-2-ol (using the official IUPAC names). Drawings were made by  molwiev.org . The antimicrobial activity of alcohols derives from their ability to denature proteins. According to the WHO, alcohol solutions containing 60–80% alcohol are the most effective  [1] . CDC claims that the most effective concentration range is between 60 and 95%   [2] . Higher concentrations are less potent, because proteins are not denatured easily in the absence of water. Alcohols have

Risk Factors for Healthcare-Associated Infections

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A recently published article,  Rodríguez-Acelas et al. 2017 ,  systematically reviewed the scientific literature, and identified risk factors for healthcare-associated infections (HAI) in hospitalized patients. What factors are proved to increase significantly the risk of HAI?